Tuesday Tip: Aspartame & Insulin 🥤
Aspartame, an artificially sweetener common in diet drinks etc, has been around for nearly 50 years, yet it’s still blamed on social media for everything from diabetes to ‘spiking’ insulin just because it tastes sweet.
The idea is that because it tastes sweet it mimics sugar and results in insulin being released, leading to fat storage, diabetes, metabolic damage etc. However the research doesn’t support this. Studies using human randomized controlled trials find that aspartame does not raise blood glucose or insulin when compared with water, placebo, or other low-calorie sweeteners. There’s no spike and therefore no crash. When aspartame is compared with sugar or other carbs, it shows a much lower glucose and insulin response with aspartame. In other words, replacing sugar with aspartame improves—not worsens—glycemic control.
What about longer-term studies? It’s the same story, even at high intakes aspartame shows no effect on fasting glucose, insulin, insulin sensitivity, or HbA1c, even in people with type 2 diabetes. Appetite hormones barely change, adverse effects are rare, and energy intake is often lower when aspartame replaces sugar.
So where does the fear come from? Mostly from misreporting animal studies using massive doses (we would need to consume hundreds of cans of diet drink per day to replicate it), or observational studies that confuse cause and effect.
Aspartame doesn’t circulate in the blood intact—it’s rapidly broken down into amino acids and tiny amounts of methanol, all at levels far below anything shown to cause harm. If aspartame truly triggered insulin without glucose, we’d see hypoglycemia. We don’t.
Replacing sugar with aspartame consistently lowers glucose and insulin exposure and the best evidence we have says it’s metabolically neutral or beneficial, not harmful. The benefits of losing weight (which swapping sugary drinks to diet drinks can help with) vastly outweigh any negatives – the biggest driver of cardiovascular disease, diabetes and mortality is obesity.
Happy Tuesday 🤗
Xx




